Proteins / MEK1 / interface with KSR1

MEK1 – KSR1

PDB PDB 7JUW (chains C/B) supported · 4 of 4 complexes MEK1 volcano ↗

Colour MEK1 (chain A) by

Interface statistics (basal)

Merged point of Fig. 6c,d: median Cohen's d of the complexes below; q is the BH-FDR of their geometric-mean p. A complex is supported at q < 0.05 and |d| ≥ 0.2. 16 interface and 101 control positions in the structure shown.

Structure shown: source

Experimental structure PDB 7JUW · X-ray, 2.88 Å · chains C/B
Crystal Structure of KSR1:MEK1 in complex with AMP-PNP
Primary citation: Khan et al., Nature 588 (2020)
RCSB Protein Data Bank (Berman et al., Nucleic Acids Res. 2000); the two chains were extracted and renumbered to UniProt (SIFTS) for this analysis.

Complexes merged into this interface

PDB 7JUW (chains C/B) (shown)
PDB 7JUX (chains C/A)
PDB 7JUY (chains C/B)
PDB 7JUZ (chains C/A)

Residue

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