Proteins / MEK1 / interface with MEK1

MEK1 – MEK1

PDB PDB 3SLS (chains B/A) · PKc_MAP2K1 #2 not supported · 0 of 2 complexes MEK1 volcano ↗

Colour MEK1 (chain B) by

Interface statistics (basal)

Merged point of Fig. 6c,d: median Cohen's d of the complexes below; q is the BH-FDR of their geometric-mean p. A complex is supported at q < 0.05 and |d| ≥ 0.2. 10 interface and 96 control positions in the structure shown.

Structure shown: source

Experimental structure PDB 3SLS · X-ray, 2.30 Å · chains B/A
Crystal Structure of human MEK-1 kinase in complex with UCB1353770 and AMPPNP
Primary citation: Meier et al., J Struct Biol 177 (2012)
RCSB Protein Data Bank (Berman et al., Nucleic Acids Res. 2000); the two chains were extracted and renumbered to UniProt (SIFTS) for this analysis.

Complexes merged into this interface

PDB 3SLS (chains B/A) · chain B (shown) · not supported
PDB 3SLS (chains B/A) · chain A · not supported

Residue

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