Proteins / GRB2 / interface with GRB2

GRB2 – GRB2

PDB PDB 2AOB (chains A/C) · SH2_GRB2_like #2 supported · 2 of 2 complexes GRB2 volcano ↗

Colour GRB2 (chain A) by

Interface statistics (basal)

Merged point of Fig. 6c,d: median Cohen's d of the complexes below; q is the BH-FDR of their geometric-mean p. A complex is supported at q < 0.05 and |d| ≥ 0.2. 6 interface and 55 control positions in the structure shown.

Structure shown: source

Experimental structure PDB 2AOB · X-ray, 1.80 Å · chains A/C
Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain
Primary citation: Phan et al., J Mol Biol 353 (2005)
RCSB Protein Data Bank (Berman et al., Nucleic Acids Res. 2000); the two chains were extracted and renumbered to UniProt (SIFTS) for this analysis.

Complexes merged into this interface

PDB 2AOB (chains A/C) · chain A (shown)
PDB 2AOB (chains A/C) · chain B

Residue

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