Proteins / MEK1 / interface with BRAF

MEK1 – BRAF

PDB PDB 6PP9 (chains A/B) not supported · 0 of 3 complexes MEK1 volcano ↗

Colour MEK1 (chain B) by

Interface statistics (basal)

Merged point of Fig. 6c,d: median Cohen's d of the complexes below; q is the BH-FDR of their geometric-mean p. A complex is supported at q < 0.05 and |d| ≥ 0.2. 18 interface and 87 control positions in the structure shown.

Structure shown: source

Experimental structure PDB 6PP9 · X-ray, 2.59 Å · chains A/B
Crystal structure of BRAF:MEK1 complex
Primary citation: Park et al., Nature 575 (2019)
RCSB Protein Data Bank (Berman et al., Nucleic Acids Res. 2000); the two chains were extracted and renumbered to UniProt (SIFTS) for this analysis.

Complexes merged into this interface

PDB 6PP9 (chains A/B) (shown) · not supported
PDB 7M0X (chains A/B) · not supported
PDB 9RTR (chains C/D) · not supported

Residue

Click a residue in the viewer.