Proteins / HGFR / interface with HGFR

HGFR – HGFR

PDB PDB 8OUU (chains B/A) · PTKc_MET_Ron supported · 4 of 4 complexes HGFR volcano ↗

Colour HGFR (chain B) by

Interface statistics (basal)

Merged point of Fig. 6c,d: median Cohen's d of the complexes below; q is the BH-FDR of their geometric-mean p. A complex is supported at q < 0.05 and |d| ≥ 0.2. 6 interface and 106 control positions in the structure shown.

Structure shown: source

Experimental structure PDB 8OUU · X-ray, 1.77 Å · chains B/A
Crystal structure of D1228V c-MET bound by compound 29
Primary citation: Michaelides et al., J Med Chem 66 (2023)
RCSB Protein Data Bank (Berman et al., Nucleic Acids Res. 2000); the two chains were extracted and renumbered to UniProt (SIFTS) for this analysis.

Complexes merged into this interface

PDB 8OUU (chains B/A) · chain B (shown)
PDB 8OUU (chains B/A) · chain A
PDB 8OUV (chains A/B) · chain A
PDB 8OUV (chains A/B) · chain B

Residue

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