Proteins / CRAF / interface with HRAS

CRAF – HRAS

PDB PDB 3KUD (chains B/A) supported · 5 of 5 complexes CRAF volcano ↗

Colour CRAF (chain A) by

Interface statistics (basal)

Merged point of Fig. 6c,d: median Cohen's d of the complexes below; q is the BH-FDR of their geometric-mean p. A complex is supported at q < 0.05 and |d| ≥ 0.2. 6 interface and 32 control positions in the structure shown.

Structure shown: source

Experimental structure PDB 3KUD · X-ray, 2.15 Å · chains B/A
Complex of Ras-GDP with RafRBD(A85K)
Primary citation: Filchtinski et al., J Mol Biol 399 (2010)
RCSB Protein Data Bank (Berman et al., Nucleic Acids Res. 2000); the two chains were extracted and renumbered to UniProt (SIFTS) for this analysis.

Complexes merged into this interface

PDB 3KUD (chains B/A) (shown)
PDB 4G0N (chains B/A)
PDB 6NTC (chains B/A)
PDB 6NTD (chains B/A)
PDB 7JHP (chains C/A)

Residue

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