Proteins / KRAS / interface with KRAS

KRAS – KRAS

PDB PDB 4TQA (chains A/B) · H_N_K_Ras_like supported · 3 of 4 complexes KRAS volcano ↗

Colour KRAS (chain A) by

Interface statistics (basal)

Merged point of Fig. 6c,d: median Cohen's d of the complexes below; q is the BH-FDR of their geometric-mean p. A complex is supported at q < 0.05 and |d| ≥ 0.2. 7 interface and 57 control positions in the structure shown.

Structure shown: source

Experimental structure PDB 4TQA · X-ray, 1.13 Å · chains A/B
Crystal Structure of a GDP-bound G13D Oncogenic Mutant of Human GTPase KRas
Primary citation: Hunter et al., Mol Cancer Res 13 (2015)
RCSB Protein Data Bank (Berman et al., Nucleic Acids Res. 2000); the two chains were extracted and renumbered to UniProt (SIFTS) for this analysis.

Complexes merged into this interface

PDB 4TQA (chains A/B) · chain A (shown)
PDB 4TQA (chains A/B) · chain B
PDB 6P0Z (chains A/B) · chain A
PDB 6P0Z (chains A/B) · chain B · not supported

Residue

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