Proteins / EGFR / interface with ERRFI1

EGFR – ERRFI1

PDB PDB 4ZJV (chains A/C) supported · 2 of 2 complexes EGFR volcano ↗

Colour EGFR (chain A) by

Interface statistics (basal)

Merged point of Fig. 6c,d: median Cohen's d of the complexes below; q is the BH-FDR of their geometric-mean p. A complex is supported at q < 0.05 and |d| ≥ 0.2. 23 interface and 75 control positions in the structure shown.

Structure shown: source

Experimental structure PDB 4ZJV · X-ray, 2.70 Å · chains A/C
crystal structure of EGFR kinase domain in complex with Mitogen-inducible gene 6 protein
Primary citation: Park et al., Nat Struct Mol Biol 22 (2015)
RCSB Protein Data Bank (Berman et al., Nucleic Acids Res. 2000); the two chains were extracted and renumbered to UniProt (SIFTS) for this analysis.

Complexes merged into this interface

PDB 4ZJV (chains A/C) (shown)
PDB 2RF9 (chains A/C)

Residue

Click a residue in the viewer.