Proteins / MRAS / interface with SHOC2

MRAS – SHOC2

PDB PDB 7TVF (chains B/A) supported · 2 of 2 complexes MRAS volcano ↗

Colour MRAS (chain A) by

Interface statistics (basal)

Merged point of Fig. 6c,d: median Cohen's d of the complexes below; q is the BH-FDR of their geometric-mean p. A complex is supported at q < 0.05 and |d| ≥ 0.2. 3 interface and 62 control positions in the structure shown.

Structure shown: source

Experimental structure PDB 7TVF · X-ray, 2.17 Å · chains B/A
Crystal structure of the SHOC2-MRAS-PP1CA (SMP) complex to a resolution of 2.17 Angstrom
Primary citation: Bonsor et al., Nat Struct Mol Biol 29 (2022)
RCSB Protein Data Bank (Berman et al., Nucleic Acids Res. 2000); the two chains were extracted and renumbered to UniProt (SIFTS) for this analysis.

Complexes merged into this interface

PDB 7TVF (chains B/A) (shown)
PDB 7TXH (chains A/B)

Residue

Click a residue in the viewer.