Proteins / MRAS / interface with PPP1CA

MRAS – PPP1CA

PDB PDB 7TVF (chains B/C) supported · 3 of 3 complexes MRAS volcano ↗

Colour MRAS (chain A) by

Interface statistics (basal)

Merged point of Fig. 6c,d: median Cohen's d of the complexes below; q is the BH-FDR of their geometric-mean p. A complex is supported at q < 0.05 and |d| ≥ 0.2. 10 interface and 54 control positions in the structure shown.

Structure shown: source

Experimental structure PDB 7TVF · X-ray, 2.17 Å · chains B/C
Crystal structure of the SHOC2-MRAS-PP1CA (SMP) complex to a resolution of 2.17 Angstrom
Primary citation: Bonsor et al., Nat Struct Mol Biol 29 (2022)
RCSB Protein Data Bank (Berman et al., Nucleic Acids Res. 2000); the two chains were extracted and renumbered to UniProt (SIFTS) for this analysis.

Complexes merged into this interface

PDB 7TVF (chains B/C) (shown)
PDB 7TXH (chains A/C)
PDB 7UPI (chains A/B)

Residue

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